国际肿瘤学杂志››2014,Vol. 41››Issue (8): 561-564.doi:10.3760/cma.j.issn.1673-422X.2014.08.001

• 综述 •下一篇

再生基因Ⅳ在肿瘤中的作用及临床应用

吴怡晨, 应莉莎, 凌志强

  1. 310022杭州,浙江省肿瘤医院肿瘤研究所
  • 收稿日期:2013-11-28修回日期:2014-03-15出版日期:2014-08-15发布日期:2014-08-14
  • 通讯作者:应莉莎,E-mail:ilonas@163.com E-mail:ilonas@163.com
  • 基金资助:

    浙江省自然科学基金(LQ13H160017)

Roles of RegⅣ in neoplasms and clinical applications

Wu Yichen, Ying Lisha, Ling Zhiqiang

  1. Cancer Research Institute, Zhejiang Province Cancer Hospital, Hangzhou 310022, China
  • Received:2013-11-28Revised:2014-03-15Online:2014-08-15Published:2014-08-14
  • Contact:Ying Lisha E-mail:ilonas@163.com

摘要:再生基因Ⅳ(RegⅣ)是再生基因家族的一员,与消化系统细胞的增殖和分化相关。RegⅣ与肿瘤的发生、发展,肿瘤细胞的增殖、侵袭以及抗凋亡等密切相关,可能是肿瘤靶向治疗潜在的分子靶标。

关键词:肿瘤,细胞增殖,治疗,再生基因Ⅳ

Abstract:As a member of regenerating isletderived family, regenerating isletderived type Ⅳ (RegⅣ) is involved in cell proliferation and differentiation. RegⅣ is closely related to the occurrence and development of tumor, tumor cell proliferation and invasion and antiapoptosis, and it may be a potential molecular target of targeting therapy in cancer.

Key words:Neoplasms,Cell proliferation,Therapy,RegⅣ