长非编码RNA在肿瘤耐药机制中的研究进展

摘要/Abstract

摘要：长非编码RNA（lncRNA）与肿瘤的发生发展、增殖迁移及临床预后密切相关，在许多肿瘤细胞发生耐药过程中起重要作用。体内外实验表明，lncRNA可以通过多种信号通路、分子作用机制来调控肿瘤细胞发生耐药，并且阻断相关靶点后可以逆转这种耐药性。

连一帆,王科明. 长非编码RNA在肿瘤耐药机制中的研究进展[J]. 国际肿瘤学杂志, 2015, 42(6): 439-441.

Lian Yifan, Wang Keming. Molecular mechanism of long non-coding RNAs in tumor drug resistance[J]. Journal of International Oncology, 2015, 42(6): 439-441.

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长非编码RNA在肿瘤耐药机制中的研究进展

Molecular mechanism of long non-coding RNAs in tumor drug resistance

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