免疫检查点抑制剂在肿瘤治疗中的不良反应及对症治疗

摘要/Abstract

摘要：免疫检查点抑制剂包括细胞毒性T淋巴细胞抗原4（CTLA4）和程序性死亡受体1（PD1）的单克隆抗体，其中抗CTLA4药物伊匹单抗、抗PD1药物帕姆单抗和纳武单抗可用于黑色素瘤和非小细胞肺癌的治疗，对肾细胞癌、膀胱癌、乳腺癌、胃肠道肿瘤等的疗效还在大规模临床试验中。这些药物在临床的应用取得了较好的效果，但是也不可避免地带来了许多不良反应。

周丽娜，李红梅. 免疫检查点抑制剂在肿瘤治疗中的不良反应及对症治疗[J]. 国际肿瘤学杂志, 2017, 44(11): 860-863.

周丽娜，李红梅. Adverse reactions and symptomatic treatment of immunological checkpoint inhibitors in tumor therapy[J]. Journal of International Oncology, 2017, 44(11): 860-863.

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免疫检查点抑制剂在肿瘤治疗中的不良反应及对症治疗

Adverse reactions and symptomatic treatment of immunological checkpoint inhibitors in tumor therapy

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