乳铁蛋白的抗肿瘤作用机制

国际肿瘤学杂志››2019,Vol. 46››Issue (5): 285-288.doi:10.3760/cma.j.issn.1673-422X.2019.05.007

莫晓媚，秦鹏飞，赵娜，闫美兴，徐鲁杰

青岛市妇女儿童医院药学部266000

收稿日期:2019-03-05出版日期:2019-05-08发布日期:2019-06-14
通讯作者:徐鲁杰 E-mail:xlujzr@126.com
基金资助:

山东省中医药科技发展计划（2015-382）；青岛市医疗卫生优秀青年医学人才培养项目（2017-9）

Anti-tumor mechanism of lactoferrin

Mo Xiaomei, Qin Pengfei, Zhao Na, Yan Meixing, Xu Lujie

Department of Pharmacy, Qingdao Women and Children′s Hospital, Qingdao 266000, China

Received:2019-03-05Online:2019-05-08Published:2019-06-14
Contact:Xu Lujie E-mail:xlujzr@126.com
Supported by:

Traditional Chinese Medicine Science and Technology Development Program of Shandong Province of China (2015-382); Medical and Health Outstanding Young Medical Talent Training Project of Qingdao City of China (2017-9)

摘要/Abstract

摘要：乳铁蛋白基因的改变与肿瘤发病率的增加有关，然而乳铁蛋白抗肿瘤作用的具体机制尚不清楚。研究发现，在不同的肿瘤细胞中，乳铁蛋白可通过破坏细胞膜、诱导细胞凋亡、阻滞细胞周期、调节细胞免疫反应以及抑制肿瘤血管生成等不同的机制影响肿瘤的发生、发展，进一步了解其机制可为临床预防和治疗肿瘤提供新的思路。

莫晓媚，秦鹏飞，赵娜，闫美兴，徐鲁杰. 乳铁蛋白的抗肿瘤作用机制[J]. 国际肿瘤学杂志, 2019, 46(5): 285-288.

Mo Xiaomei, Qin Pengfei, Zhao Na, Yan Meixing, Xu Lujie. Anti-tumor mechanism of lactoferrin[J]. Journal of International Oncology, 2019, 46(5): 285-288.

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