二甲双胍的抗肿瘤作用

摘要/Abstract

摘要：二甲双胍作为一种廉价安全高效的糖尿病药物已应用多年，近年来研究显示其对各种肿瘤细胞都有不同程度的抑制作用。二甲双胍的抗肿瘤机制尚未完全明确，可能与糖代谢及蛋白激酶途径有关，也可能与炎症因子介导肿瘤杀伤有关。二甲双胍对不同肿瘤细胞杀伤效果不同，对其他抗肿瘤治疗也有一些辅助作用。

郭延勋；马士崟. 二甲双胍的抗肿瘤作用[J]. 国际肿瘤学杂志, 2015, 42(4): 281-283.

GUO Yan-Xun-；Ma-Shi-Yin. Antitumor effects of metformin[J]. Journal of International Oncology, 2015, 42(4): 281-283.

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