国际肿瘤学杂志››2017,Vol. 44››Issue (4): 278-280.doi:10.3760/cma.j.issn.1673-422X.2017.04.009

• 综述 •上一篇下一篇

c-Myc在肿瘤中的表达及功能

俞今晶,来纯云

  1. 100853 北京,解放军总医院呼吸科
  • 出版日期:2017-04-08发布日期:2017-05-09
  • 通讯作者:来纯云 E-mail:laicyxx3013@sina.com

Expression and function of c-Myc in tumor

Yu Jinjing, Lai Chunyun

  1. Department of Respiratory Diseases, General Hospital of PLA, Beijing 100853, China
  • Online:2017-04-08Published:2017-05-09
  • Contact:Lai Chunyun E-mail:laicyxx3013@sina.com

摘要:原癌蛋白c-Myc在多种组织和细胞中均有表达,其功能的异常与淋巴瘤、前列腺癌、乳腺癌、胰腺癌等多种肿瘤的发生和预后密切相关。随着对c-Myc在肿瘤中的表达及功能研究的不断深入,通过靶向c-Myc治疗肿瘤取得了较大进展。

关键词:肿瘤,原癌基因蛋白质c-myc,靶向治疗

Abstract:The proto oncogene c-Myc is expressed in many kinds of organs, and its dysfunction is closely related to the occurrence and prognosis of lymphoma, prostatic cancer, breast cancer and pancreatic cancer. With a large number of studies focus on the expression and function of c-Myc in tumor, the treatment of tumor by targeting c-Myc has made a wealth of progress.

Key words:Neoplasms,Proto-oncogene proteins c-myc,Targeted treatment