免疫微环境在宫颈癌中的研究进展

摘要/Abstract

摘要：

淋巴细胞亚群、肿瘤相关巨噬细胞等作为肿瘤微环境中主要的免疫细胞，与其分泌的细胞因子相互作用共同构成免疫微环境，已成为宫颈癌复发转移的重要参与者，亦可影响宫颈癌同步放化疗的敏感性，进而影响患者的疗效和预后。近年来以免疫微环境为基础的宫颈癌免疫和靶向治疗已成为宫颈癌领域的研究热点。

关键词:宫颈肿瘤,肿瘤微环境,化放疗,免疫疗法

Abstract:

Lymphocyte subsets and tumor-associated macrophages， which are the primary immune cells in the tumor microenvironment， interacts with its released cytokines to form the immunological microenvironment. It has grown to be a significant factor in the recurrence and metastasis of cervical cancer and influences the effectiveness of concurrent radiotherapy and chemotherapy for the disease， which in turn influences the prognosis and outcome of patients. Immunotherapy and targeted therapy for cervical cancer based on the immune microenvironment have grown in popularity as research topics in recent years.

Key words:Uterine cervical neoplasms,Tumor microenvironment,Chemoradiotherapy,Immunotherapy

马雪艳, 鲁历历, 孙鹏飞. 免疫微环境在宫颈癌中的研究进展[J]. 国际肿瘤学杂志, 2023, 50(1): 47-50.

Ma Xueyan, Lu Lili, Sun Pengfei. Advances in the immune microenvironment in cervical cancer[J]. Journal of International Oncology, 2023, 50(1): 47-50.

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