Abstract:Lysyl oxidase-like protein 2 (LOXL2) is one of the lysyl oxidases (LOX) families. At present, most of scholars consider that LOXL2 is a neoplasm metastasis gene, whereas some others believe that LOXL2 is a neoplasm suppressor gene. Studies found that LOXL2 gene combined with other oncogenes promotes neoplasm invasion, metastasis and indicates a poor prognosis. Related researches provide new ideas for judging tumor metastasis and prognosis and looking for new targets for cancer therapy.

Key words:font-family: "Times New Roman",mso-font-kerning: 1.0pt,mso-ansi-language: EN-US,mso-fareast-language: ZH-CN,mso-bidi-language: AR-SA,mso-fareast-font-family: 宋体">Protein-lysine 6-oxidase,color: #313131">Neoplasms,font-family: "Times New Roman",mso-ansi-language: EN-US,mso-fareast-language: ZH-CN,mso-bidi-language: AR-SA,mso-fareast-font-family: 宋体">Lysyl oxidase-likebackground: white,color: black,font-family: "Times New Roman",mso-bidi-font-size: 11.5pt,mso-font-kerning: 1.0pt,mso-ansi-language: EN-US,mso-fareast-language: ZH-CN,mso-bidi-language: AR-SA,mso-fareast-font-family: 宋体">protein 2