Journal of International Oncology››2012,Vol. 39››Issue (5): 359-362.

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Drug resistance related factors and cancer metastasis

HUANG Zi-qi, LU Lie-sheng, DING Wei-xing.

  1. Department of Gastrointestinal Surgery, Shanghai Tenth People′s Hospital, Shanghai Tongji University of Medicine, Shanghai 200072, China
  • Online:2012-05-08Published:2012-05-02
  • Contact:DING Wei-xing, E-mail: dwxing@medmail.com.cn E-mail:dwxing@medmail.com.cn

Abstract:As multidrug resistance related genes and cell factors are discovered one after another, people have a more thorough understanding to the oncological mechanisms of cancer metastasis. Many evidences of the inherent link between the two tips have been found. These researches provide new ideas to further clarify the regulation mechanisms between them. It is revealed that the inherent link maybe occur on the gene expression and transcription, and with complicated regulative factors. Indepth study of the relations between cancer multidrug resistance and metastasis will help to guide the clinical treatment of tumor.

Key words:Drug resistance, neoplasm,Drug resistance, multiple,Neoplasm invasiveness,Neoplasm metastasis