Journal of International Oncology››2014,Vol. 41››Issue (12): 887-890.doi:10.3760/cma.j.issn.1673-422X.2014.12.003

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Research progress of miR-451 in tumor

  1. Department of Neurosurgery, Tianjin Medical University General Hospital;Laboratory of Neurooncology,Tianjin Neurological Institute, Tianjin 300052,China
  • Online:2014-12-24Published:2015-02-02
  • Contact:Zhong Yue, Email: zhongyue2457@sina.com

Abstract:MicroRNA451(miR451) is significantly lowly expressed in glioma, gastric cancer, colorectal cancer, liver cancer and other tumor tissues. Upregulation of miR451 can significantly inhibit tumor cell proliferation,invasion and metastasis as well as increasing tumor cell apoptosis and improving radiotherapy and chemotherapy sensitivity and other biological effects.

Key words:Neoplasms; ,MicroRNAs