纤维支气管镜吸痰灌洗治疗对重症肺炎患者的疗效及炎症标志物水平的影响

betway必威登陆网址（betway.com ）学报››2021,Vol. 42››Issue (3): 203-206.DOI:10.3969/j.issn.1004-7115.2021.03.010

纤维支气管镜吸痰灌洗治疗对重症肺炎患者的疗效及炎症标志物水平的影响

张晓, 高芸, 李雪华, 田红

betway必威登陆网址第二附属医院呼吸与危重症医学科,山东泰安 271000

收稿日期:2020-11-08出版日期:2021-03-25发布日期:2021-09-01
通讯作者:田红,主任医师,硕士研究生导师,E-mail:mjyth@126.com。
作者简介:张晓,硕士研究生,研究方向:肺部感染,E-mail:zhangxiao0808@126.com。

The effect of fiberoptic bronchoscope suction and lavage treatment on patients with severe pneumonia and the effect of inflammation markers

ZHANG Xiao, GAO Yun, LI Xue-hua, TIAN Hong

Dept. of Respiratory and Critical Care Medicine, the Second Affiliated Hospital of Shandong First Medical University, Taian 271000, China

Received:2020-11-08Online:2021-03-25Published:2021-09-01

摘要/Abstract

摘要：目的研究重症肺炎患者采用纤维支气管镜吸痰方式实施辅助性治疗的临床效果。方法选择我院收治的42例重症肺炎患者,通过随机分组的方式分成对照组和治疗组,每组21例。对照组实施常规抗感染及对症治疗;治疗组在常规抗感染及对症治疗的基础上,采用纤维支气管镜吸痰方式实施辅助性治疗,根据病情需要每日或隔日给予1次治疗,持续1周。比较两组治疗前后炎症标志物降钙素原(PCT)、C-反应蛋白(CRP)水平,病情控制总有效率、住院总时间。结果治疗组患者治疗前后炎症标志物水平的改善幅度大于对照组;病情控制总有效率达到90.5%,高于对照组的71.4%;住院总时间为(9.16±1.02)d,低于对照组的(13.62±2.45)d,组间差异均有统计学意义(P＜0.001)。结论重症肺炎患者采用纤维支气管镜吸痰方式实施辅助性治疗,能够大幅度改善炎症标志物水平,缩短住院治疗总时间,使疾病治疗的总有效率提高。

关键词:重症肺部感染,纤维支气管镜,吸痰,灌洗治疗,炎症标志物

Abstract:Objective: To study the clinical effect of auxiliary treatment by means of sputum suction with fiberoptic bronchoscope in patients with severe pneumonia. Methods: Forty-two patients with severe pneumonia in our hospital were randomly divided into control group and treatment group, with an average of 21 cases in each group. The control group received conventional anti infection and symptomatic treatment; the treatment group received auxiliary treatment by fiberoptic bronchoscope sputum suction on the basis of conventional anti infection and symptomatic treatment, and was given once a day or every other day according to the needs of the state of the illness,lasting for 1 week.And the levels of inflammatory markers (procalcitonin PCT, C-reactive protein CRP), the total effective rate of disease control and the total length of hospital stay were compared between the two groups before and after treatment. Results: The improvement of inflammatory markers in the treatment group was greater than that in the control group after the treatment. The total effective rate of disease control was 90.5%, which was higher than 71.4%,the rate of the control group; the total hospitalization time was (9.16± 1.02) d, which was lower than (13.62± 2.45) d in the control group, and the difference between the two groups was statistically significant(P＜0.001). Conclusion: In patients with severe pneumonia, auxiliary treatment by means of sputum aspiration with fiberoptic bronchoscope can significantly improve the level of inflammatory markers, shorten the total length of hospital treatment, and improve the total effective rate of disease treatment.

Key words:severe lung infection,fiberoptic bronchoscopy,sputum suction,lavage treatment,inflammation markers

中图分类号:

R563

张晓, 高芸, 李雪华, 田红. 纤维支气管镜吸痰灌洗治疗对重症肺炎患者的疗效及炎症标志物水平的影响[J]. betway必威登陆网址（betway.com ）学报, 2021, 42(3): 203-206.

ZHANG Xiao, GAO Yun, LI Xue-hua, TIAN Hong. The effect of fiberoptic bronchoscope suction and lavage treatment on patients with severe pneumonia and the effect of inflammation markers[J]. Journal of Shandong First Medical Unversity & Shandong Academy of Medical Sciences, 2021, 42(3): 203-206.

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