betway必威登陆网址 (betway.com )学报 ›› 2021, Vol. 42 ›› Issue (3): 225-227.DOI: 10.3969/j.issn.1004-7115.2021.03.016

• 论著 • 上一篇    下一篇

低温等离子射频消融术治疗早期声门型喉癌的近期临床疗效观察

杨美艳   

  1. 巨野县人民医院耳鼻喉科,山东 巨野 274900
  • 收稿日期:2020-11-17 出版日期:2021-03-25 发布日期:2021-09-01
  • 作者简介:杨美艳,副主任医师,本科,主要从事耳鼻咽喉科临床诊治工作,E-mail:544203909@qq.com。

Clinical observation of low temperature plasma radiofrequency ablation in the treatment of early glottic carcinoma

YANG Mei-yan   

  1. Dept. of Otorhinolaryngology, Juye County People's Hospital, Juye 274900, China
  • Received:2020-11-17 Online:2021-03-25 Published:2021-09-01

摘要: 目的 探讨低温等离子射频消融术治疗早期声门型喉癌患者近期临床疗效。方法 随机选取我院于2018年6月至2020年5月间收治的80例早期声门型喉癌患者,按照手术方式不同分为观察组与对照组,每组各40例。对照组采取垂直半喉切除术,观察组采取低温等离子射频消融术,评估并比较两组患者临床疗效及其并发症发生率;比较两组患者术前,术后1周、1月嗓音学检测的基频微扰(jitter)、振幅微扰(shimmer)、谐噪比(HNR)。结果 与对照组相比,观察组手术时间、住院时间更短,且术中出血量更少,差异有统计学意义(P<0.05);观察组并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论 低温等离子射频消融术对早期声门型喉癌患者疗效确切,可在提高手术效果的同时,降低术后并发症发生率,提高患者的生活质量。

关键词: 低温等离子射频消融术, 早期声门型喉癌, 疗效

Abstract: Objective: To investigate the clinical efficacy and complication rate of low temperature plasma radiofrequency ablation in the treatment of early glottic carcinoma. Methods: Eighty patients with early glottic carcinoma in our hospital from June 2018 to may 2020 were randomly selected and divided into observation group and control group according to different surgical methods, with 40 cases in each group. The control group was treated with vertical hemilaryngectomy, and the observation group was treated with low-temperature plasma radiofrequency ablation. The clinical efficacy and the incidence of complications of the two groups were evaluated and compared; the preoperative and postoperative complications of the two groups were compared. The fundamental frequency perturbation (jitter), amplitude perturbation (shimmer) and harmonic to noise ratio (HNR) of the two groups were measured at 1 week and 1 month after treatment. Results: Compared with the control group, the operation time and hospitalization time of the observation group were shorter, and the intraoperative blood loss was less, and the difference was statistically significant (P<0.05); the incidence of complications in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Low temperature plasma radiofrequency ablation is effective for patients with early glottic carcinoma and it can improve the surgical effect, reduce the incidence of postoperative complications and improve the quality of life of patients.

Key words: low temperature plasma radiofrequency ablation, early glottic carcinoma, efficacy

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