高迁移率族蛋白A1在肿瘤发生发展中的作用

摘要/Abstract

摘要：高迁移率族蛋白A1（HMGA1）是一种非组蛋白的染色质相关蛋白，可以通过多种途径对肿瘤相关基因进行转录调控，进而影响肿瘤的发生发展。HMGA1不仅可以作为肿瘤的标志物，而且还可作为肿瘤的预后指标和治疗靶点，为肿瘤生物治疗提供了新途径。

王运良, 李翠, 贾喜花等. 高迁移率族蛋白A1在肿瘤发生发展中的作用[J]. 国际肿瘤学杂志, 2014, 41(1): 14-17.

WANG Yun-Liang, LI Cui, JIA Xi-Hua, et al. Role of high mobility group protein A1 in tumor development[J]. Journal of International Oncology, 2014, 41(1): 14-17.

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高迁移率族蛋白A1在肿瘤发生发展中的作用

Role of high mobility group protein A1 in tumor development

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