复发高级别胶质瘤的诊断和治疗

摘要/Abstract

摘要：高级别胶质瘤是一种常见的侵袭性极高的恶性脑肿瘤，而且普遍存在初次治疗后进展和极高的死亡率。早期诊断肿瘤复发及选择高度个体化的治疗对于延长患者生存期有重要意义。多模态磁共振及分子影像学在鉴别诊断胶质瘤复发、预后评估等方面具有重要价值。再手术、再放疗、电场治疗、化疗、靶向治疗、免疫治疗等局部、全身治疗策略有望为复发高级别胶质瘤患者带来生存获益。

关键词:神经胶质瘤,复发,高级别

Abstract:High grade glioma is a kind of malignant brain tumor with strong invasiveness, which progresses commonly after initial treatments and shows high mortality. Early diagnosis of tumor recurrence and highlyindividualized systemic treatment mean significance to prolong survival. Multimode magnetic resonance imaging and molecular imaging play important roles in differential diagnosis and prognosis evaluation for recurrence. Therapeutic strategies like reoperation, reirradiation, electric field technology, chemotherapy, targeted therapies and immunotherapeutic approaches are expected to bring survival benefits for patients with recurrent high grade glioma.

Key words:Glioma,Recurrence,Highgrade

刘雪,任庆兰. 复发高级别胶质瘤的诊断和治疗[J]. 国际肿瘤学杂志, 2017, 44(10): 767-770.

Liu Xue, Ren Qinglan. Diagnosis and treatment of recurrent high grade glioma[J]. Journal of International Oncology, 2017, 44(10): 767-770.

参考文献

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