国际肿瘤学杂志

国际肿瘤学杂志››2012,Vol. 39››Issue (5): 344-347.

• 综述 •上一篇下一篇

细胞因子诱导的杀伤细胞在肿瘤治疗中的作用

梁雪峰，丁震宇，谢晓冬

  1. 沈阳军区总医院全军肿瘤诊治中心肿瘤科
  • 出版日期:2012-05-08发布日期:2012-05-02
  • 通讯作者:谢晓冬，Email：xiexiaodong@csco.org.cn E-mail:xiexiaodong@csco.org.cn

Cytokineinduced killer cells in cancer treatment

LIANG Xue-feng, DING Zhen-yu, XIE Xiao-dong

  1. Department of Oncology, Cancer diagnosis and treatment center of PLA, General Hospital of Shenyang Military Region, Shenyang 110840, China
  • Online:2012-05-08Published:2012-05-02
  • Contact:XIE Xiao-dong, E-mail: xiexiaodong@csco.org.cn E-mail:xiexiaodong@csco.org.cn

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2125

被引次数

9

摘要：细胞因子诱导的杀伤细胞（CIK）治疗是在手术、化疗和放疗之后的第4大肿瘤治疗手段，是目前肿瘤治疗的发展方向。它是一种新型的免疫活性细胞，该种细胞同时表达CD3和CD56两种膜蛋白分子，因此又将其称之为自然细胞杀伤样T淋巴细胞。CIK在临床应用比较广泛，在血液系统肿瘤、实体瘤的治疗中都取得了较好的临床疗效，是抗肿瘤过继免疫治疗的新希望。

关键词:杀伤细胞,肿瘤,免疫疗法

Abstract:Cytokineinduced killer cells (CIK) is the fourth largest cancer treatment after surgery, chemotherapy and radiotherapy, and it is the development direction of cancer treatment. It is a new type of immune cell, and it is named after natural killer cell samples T lymphocytes as it express CD3 and CD56. Currently, CIK treatment has a broader range of clinical applications, and it has achieved the better clinical efficacy in the blood system cancer and solid tumors. The CIK adoptive immunotherapy is considered to be a new hope for the anticancer treatment.

Key words:Killer cells,Neoplasms,Immunotherapy