国际肿瘤学杂志

国际肿瘤学杂志››2013,Vol. 40››Issue (1): 15-18.

• 综述 •上一篇下一篇

结肠癌转移相关基因1与肿瘤

李祯, 生秀杰

  1. 510150广州医学院第三附属医院妇产科研究所广东省普通高校生殖与遗传重点实验室
  • 出版日期:2013-01-08发布日期:2013-01-15
  • 通讯作者:生秀杰，E-mail: xjsheng@gzemail.cn E-mail:xjsheng@gzemail.cn

Metastasis-associated in colon cancer-1 and tumor

LI Zhen, SHENG Xiu-Jie

  1. Department of Gynecology,the Third Affiliated Hospital of Guangzhou Medical College,Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
  • Online:2013-01-08Published:2013-01-15
  • Contact:Corresponding author: SHENG Xiu-jie, E-mail: xjsheng@gzemail.cn E-mail:xjsheng@gzemail.cn

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被引次数

1

摘要：结肠癌转移相关基因1（MACC1）为新近发现的调节肿瘤生长和转移的基因，在多种恶性肿瘤中异常表达，其编码蛋白作为HGF-MET信号通路的一个关键调节因子，可明显增强肿瘤细胞的侵袭及转移能力。

关键词:结肠癌转移相关基因1,肿瘤,肿瘤转移

Abstract:Metastasis-associated in colon cancer-1 (MACC1), a newly discovered gene which controls tumor growth and metastasis, abnormally expressed in a variety of malignant tumors. As a key regulator of HGF-MET signal pathway, its coding protein can obviously promote invasion and metastasis of tumor cells.

Key words:Metastasis-associated in colon cancer-1,Neoplasms,Neoplasm metastasis