Hedgehog通路在大肠癌中的作用

摘要/Abstract

摘要：Hedgehog（Hh）信号通路与人类多种肿瘤的发生密切相关，已有研究报道Hh通路在大肠癌的发生、转移和治疗中均起到重要作用。目前在大肠癌组织和细胞中都检测到了Hh通路相关成员的高表达，抑制此通路后大肠癌细胞的侵袭和转移能力明显降低，以Hh通路为靶点治疗大肠癌已成为当前研究的热点。

毕研贞,孔令斌. Hedgehog通路在大肠癌中的作用[J]. 国际肿瘤学杂志, 2016, 43(1): 64-66.

Bi Yanzhen, Kong Lingbin. The role of Hedgehog pathway in colorectal cancer[J]. Journal of International Oncology, 2016, 43(1): 64-66.

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The role of Hedgehog pathway in colorectal cancer

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