外泌体在肿瘤形成及诊疗中的作用

摘要/Abstract

摘要：外泌体是正常细胞与肿瘤细胞均会分泌的膜性亚细胞结构，内含多种特定微小RNA（miRNA）及信号分子，在肿瘤的形成机制、诊断分型以及免疫治疗中均具有重要研究价值。外泌体对肿瘤发生发展具有双刃剑作用，其内含的miRNA作为分子标记有助于对胶质母细胞瘤等形态学上疑难的肿瘤进行分型，而在肿瘤治疗中，外泌体既可以作为药物载体，又可以通过自身特性实现新型免疫治疗。

杨鑫，孟斌. 外泌体在肿瘤形成及诊疗中的作用[J]. 国际肿瘤学杂志, 2018, 45(12): 739-742.

Yang Xin, Meng Bin. Roles of exosomes in tumor formation, diagnosis and treatment[J]. Journal of International Oncology, 2018, 45(12): 739-742.

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外泌体在肿瘤形成及诊疗中的作用

Roles of exosomes in tumor formation, diagnosis and treatment

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