国际肿瘤学杂志››2012,Vol. 39››Issue (6): 455-458.

• 综述 •上一篇下一篇

肿瘤与静脉血栓栓塞症

石志永,张沂平

  1. 杭州,浙江省肿瘤医院化疗中心
  • 出版日期:2012-06-08发布日期:2012-06-25
  • 通讯作者:张沂平,E-mail:zyp@medmail.com.cn E-mail:zyp@medmail.com cn

Cancer and venous thromboembolism

SHI Zhi-yong, ZHANG Yi-ping

  1. Chemotherapy Centre, Zhejiang Cancer Hospital, Hangzhou 310022, China
  • Online:2012-06-08Published:2012-06-25
  • Contact:ZHANG Yi-ping, E-mail: zyp@medmail.com cn E-mail:zyp@medmail.com cn

摘要:肿瘤患者有较高的静脉血栓发生率。研究发现,静脉血栓栓塞症(VTE)可增加肿瘤患者的死亡风险。VTE的发生机制与组织因子(TF)及癌促凝物质(CP)等因素密切相关。患者相关性因素、肿瘤相关性因素及治疗相关性因素均可导致患者VTE发生率增加。应重视对患者危险因素进行评估,对高危患者及早进行预防性抗凝治疗,在诊断VTE后应立即进行急性期治疗及慢性期维持治疗。

关键词:肿瘤,静脉血栓形成

Abstract:Thrombosis disease is a common complication of cancer. Researches show that venous thromboembolism (VTE) can increase the mortality rate of patients with cancer. Tissue factor (TF) and cancer procoagulant (CP) and other pathological factors are related to VTE. VTE risk factors in cancer patients can be grouped into 3 general categories: patientrelated factors, cancer-related factors and treatmentrelated factors. Assessment of risk factors and early prevention can reduce the incidence of VTE. Immediate treatment and chronic therapy should be performed immediately after the diagnosis of VTE.

Key words:Neoplasms,Venous thrombosis