betway必威登陆网址 (betway.com )学报››2023,Vol. 44››Issue (7): 522-525.DOI:10.3969/j.issn.2097-0005.2023.07.009

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心肌炎中的诊断标志物研究进展

杨儒林1(), 韩波1,2()

  1. 1.山东大学齐鲁医学院,山东 济南 250012
    2.betway必威登陆网址 附属省立医院小儿心脏科,山东 济南 250021
  • 收稿日期:2023-03-01出版日期:2023-07-25发布日期:2023-09-12
  • 通讯作者:韩波
  • 作者简介:杨儒林,硕士研究生,研究方向:小儿心脏,E-mail:17865196760@163.com
  • 基金资助:
    国家自然科学基金面上项目(81873498)

Advances in the study of diagnostic markers in myocarditis

Rulin YANG1(), Bo HAN1,2()

  1. 1.Cheeloo College of Medicine,Shandong University,Jinan 250012,China
    2.Department of Pediatrics,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China
  • Received:2023-03-01Online:2023-07-25Published:2023-09-12
  • Contact:Bo HAN

摘要:

心肌炎是一种心脏炎症性疾病,由于缺乏特异性的诊断标志物,心肌炎的诊断主要依赖于临床诊断。传统的生物标志物虽然具有较高的灵敏度,但缺乏特异性。随着对非编码RNA(non-coding RNA,ncRNA)的研究探索,其在心肌炎诊断方面的作用逐渐被发现,其中不乏具有较高灵敏度和特异性的生物标志物。本研究旨在描述心肌炎诊断的现状及有关ncRNA作为心肌炎诊断标志物的研究进展。

关键词:心肌炎,暴发性心肌炎,非编码RNA,生物标志物

Abstract:

The diagnosis of myocarditis, an inflammatory disease of the heart, has been dependent on clinical diagnosis due to the lack of specific diagnostic markers, and traditional biomarkers have high sensitivity but lack specificity. With the study of non-coding RNA (ncRNA), its role in the diagnosis of myocarditis has been gradually studied, and there are many biomarkers with high sensitivity and specificity. The purpose of this article is to describe the current status of myocarditis diagnosis and the progress of research on ncRNA as a diagnostic marker for myocarditis.

Key words:myocarditis,fulminant myocarditis,non-coding RNA,biomarkers