阻塞性睡眠呼吸暂停与心房颤动的关系研究进展

摘要/Abstract

摘要：

阻塞性睡眠呼吸暂停（obstructive sleep apnea，OSA）在心房颤动（atrial fibrillation，AF）患者中非常普遍，在AF的发病机制中起着重要作用。AF患者中OSA的存在与症状的严重程度和住院风险增加有关。此外，未经治疗的OSA与消融或心律转复后AF复发的风险增加相关。观察性研究表明，持续气道正压（continuous positive airway pressure，CPAP）治疗可以降低这种风险。本文就OSA和AF之间关系、OSA诱发AF的可能机制以及CPAP治疗作一综述，为OSA合并AF患者的临床治疗提供新思路。

关键词:阻塞性睡眠呼吸暂停,心房颤动,心房重构,持续气道正压通气

Abstract:

Obstructive sleep apnea （OSA） is very common in patients with atrial fibrillation （AF） and plays an important role in the pathogenesis of AF. The presence of OSA in AF patients was associated with increased symptom severity and risk of hospitalization. In addition， untreated OSA was associated with an increased risk of AF recurrence after ablation or cardioversion. Observational studies have shown that continuous positive airway pressure （CPAP） therapy can reduce this risk. This article reviews the relationship between OSA and AF， the possible mechanism of OSA induced AF and the treatment of CPAP， so as to provide new ideas for the clinical treatment of OSA patients with AF.

Key words:obstructive sleep apnea,atrial fibrillation,atrial remodeling,continuous positive airway pressure

邵宝兴, 郝燕. 阻塞性睡眠呼吸暂停与心房颤动的关系研究进展[J]. betway必威登陆网址（betway.com ）学报, 2023, 44(12): 945-949.

Baoxing SHAO, Yan HAO. Relationship of obstructive sleep apnea with atrial fibrillation and continuous positive airway pressure therapy[J]. Journal of Shandong First Medical Unversity & Shandong Academy of Medical Sciences, 2023, 44(12): 945-949.

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